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Exemestane/Aromasin

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the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
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Exemestane
Alias: Aromasin ; Exemestan
CAS NO: 107868-30-4
MF: C20H24O2
MW: 296.4
Purity: 99%
Appearance: white solid powder.


Applications:
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.


Specifications:

TEST ITEMS

SPECIFICATION

RESULTS

Description

: White Crystalline Powder

White Powder

Identification

:  Positive

Positive

Assay(by HPLC)

:  98.0~102.0%

98.64%

Absorbance(E1cm)

:  465~495

482.5

Melting Point

:  191~195°C

193.5~195.0°C

Loss On Drying

:  0.5%max

0.19%

Specific Rotation

:  +288°~ +298°

+290.2°

Residue On Ignition

:  0.1%max

0.03%

Related Substances

:  Total:1.5%max

<1.3%

 

Single:0.5%max

<0.4%

Residue Solvents

:  0.2%max

0.10%

Heavy Metals

:  20PPm max

<10PPm

 

 

 

Conclusion

The specification conform with enterprise standard.



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