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Finasteride/Proscar

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Finasteride is an orally active testosterone Type II 5-alpha reductase inhibitor, inhibiting the enzyme that converts testosterone to dihydrotestosterone (DHT).
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Finasteride

Alias: Proscar

CAS No: 98319-26-7

MF: C23H36N2O2

MW: 372.55

Purity: 98.5%

Appearance:  white powder.

 

Applications:

Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) in men. Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually loss moderately.
 

Used for the treatment of prostate disease first. Clinical studies suggest that, with finasteride 1 mg/day, continuous oral 3 months or slightly long can have hair growth, after continuous treatment 1 year hair growth rate to 48%, and can continue to fall off, taking the hair organization 2 years hair growth rate reached 66% ~ 83%.

 

Specifications:

Test Items

Specification

Test Results

Description

White or off-white crystalline powder

Off-white crystalline powder

Specific rotation

-56°~-60°

-58.2°

Identification

IR

Matches with working standard

Complies

HPLC

Solubility

Freely soluble in chloroform and in alcohol; Very slightly soluble in water

Conform

Heavy metals

≤10ppm

<10ppm

Water

≤0.3%

0.22%

Residue on ignition

≤0.1%

0.05%

Relative material

Maximum impurities≤0.5%

0.36%

Total impurities≤1.0%

0.52%

Assay

98.5~101.0%

99.4%

Conclusion

The specification conform with USP29





 
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