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Ibutamoren MK677

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a promising therapy for the treatment of frailty in the elderly
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  • Description
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MK-677(Ibutamoren) Nutrobal

Cas No: 159634-47-6;159752-10-0
MF: C27H36N4O5S.CH4O3S
MW: 624.776

Assay: 99%
Appearance: Kind of white powder

Application: 
a growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly.
Increase the production of growth hormone, tighten the skin to improve sleep quality, increase appetite, increase muscle mass and fat oxidation, and help the healing of ligaments, bones and tendons.

 

How it works? 

According to scientific studies based on animal test subjects, the chief function behind MK-677 is to boost the production increase of the following substances:

Ghrelin

IGF-1

Ghrelin is a self-regulated 28 amino acid chain that is primarily produced by the stomach, although it can also be secreted by the epsilon cells that are found within the pancreas.  The main function behind the secretion of ghrelin is to stimulate the sensation of being hungry.  The enzyme serves as a counter to the enzyme secretion leptin, which is produced to stimulate the sensation of being full.  The increase in the production of ghrelin can cause an animal test subject to want to consume more food, and it can allow this desire to eat to come through a more efficient means.  It can also mean that the animal test subject will experience a greater capacity to intake a greater amount of food in one setting.

 

IGF-1, on the other hand, is a secretion that is short for Insulin Growth Factor-1.  It is a protein that is secreted by the liver of animal test subjects. The relationship between ghrelin and IGF-1 is symbiotic.  As the animal test subject is given an increased capacity to consume more food for fuel because of the secretion of ghrelin, the secretion of IGF-1 allows the increased fuel that is converted to be distributed to muscular and skeletal cells on a more efficient basis.  Ultimately, this boost in protein synthesis that is caused by the increase of both ghrelin and IGF-1 as brought about by MK-677 allows the animal test subject to achieve a level of homeostasis on a substantially more efficient basis in terms of protein synthesis.

 

Dosages and Suggestion

Recommended maximum dose IBUTAMORIN about 25mgs-50mgs is the oral dose for that men,, females and 12.5 mg. It has a half-life of 24 hours a day.

 

Specifications: COA

Item Specification Result
Appearance An odorless, almost white or white powder pass
Identification The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 0.5% 0.33%
Assay(HPLC) Not less than 99.0% 99.2%
Ignition residue Not more than 0.1% pass
Heavy metal Not more than 20 ppm pass


HPLC:


 

Average rating: 5.0 based on 86 reviews
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